The book presents a new way of understanding Darwinism and evolution by natural selection, combining work in biology, philosophy, and other fields.

This book explains the relationship between intelligence and environmental complexity, and in so doing links philosophy of mind to more general issues about the relations between organisms and environments, and to the general pattern of 'externalist' explanations. The author provides a biological approach to the investigation of mind and cognition in nature. In particular he explores the idea that the function of cognition is to enable agents to deal with environmental complexity. The history of the idea in the work of (...) Dewey and Spencer is considered, as is the impact of recent evolutionary theory on our understanding of the place of mind in nature. (shrink)

v. 1. Nicomachean ethics. Politics. The Athenian Constitution. Rhetoric. On Poetics.--v. 2. Logic.--v. 3. Physics. Metaphysics. On the soul. Short physical treaties.--v. 4. On the heavens. On generation and corruption. Meteorology. Biological treatises.

Biological functions are dispositions or effects a trait has which explain the recent maintenance of the trait under natural selection. This is the "modern history" approach to functions. The approach is historical because to ascribe a function is to make a claim about the past, but the relevant past is the recent past; modern history rather than ancient.

them. Though Aristotle does not say so, presumably the questioner who conceals in this way must be prepared, when challenged, to show that the conclusion...

Non-actual model systems discussed in scientific theories are compared to fictions in literature. This comparison may help with the understanding of similarity relations between models and real-world target systems. The ontological problems surrounding fictions in science may be particularly difficult, however. A comparison is also made to ontological problems that arise in the philosophy of mathematics.

One way to express the most persistent part of the mind-body problem is to say that there is an “explanatory gap” between the physical and the mental. The gap is not usually taken to apply to all of the mental, but to subjective experience, the mind’s “qualitative” features, or what is now referred to as “phenomenal consciousness.” The “gap” formulation is due to Joseph Levine. He acknowledged the appeal of intuitions of separability between physical facts, of any kind we can (...) envisage, and this aspect of our mental lives. Subjective experience seems not to be the sort of thing that is just the physical under another guise. The immediate focus of Levine’s discussion was a family of arguments due to Saul Kripke. Kripke argued that some influential claims of mind-body identity could not be, as materialists claimed, contingent. If these identities are real then they are necessary. But we can clearly conceive that the mental and physical could come apart—an intuition that “identity theorists” conceded. Given that the identity is necessarily present if present at all, from the fact it is not necessary we can see it is absent. Kripke concluded that physicalism is false. Levine wanted to resist this. (shrink)

The paper links discussions of two topics: biological individuality and the simplest forms of mentality. I discuss several attempts to locate the boundary between metabolic activity and ‘minimal cognition.’ I then look at differences between the kinds of individuality present in unicellular life, multicellular life in general, and animals of several kinds. Nervous systems, which are clearly relevant to cognition and subjectivity, also play an important role in the form of individuality seen in animals. The last part of the paper (...) links these biological transitions to the evolutionary history of subjective experience. (shrink)

I argue that everyday folk-psychological skill might best be explained in terms of the deployment of something like a model, in a specific sense drawn from recent philosophy of science. Theoretical models in this sense do not make definite commitments about the systems they are used to understand; they are employed with a particular kind of flexibility. This analysis is used to dissolve the eliminativism debate of the 1980s, and to transform a number of other questions about the status and (...) role of folk psychology. (shrink)

The concept of information has acquired a strikingly prominent role in contemporary biology. This trend is especially marked within genetics, but it has also become important in other areas, such as evolutionary theory and developmental biology, particularly where these fields border on genetics. The most distinctive biological role for informational concepts, and the one that has generated the most discussion, is in the description of the relations between genes and the various structures and processes that genes play a role in (...) causing. For many biologists, the causal role of genes should be understood in terms of their carrying information about their various products. That information might require the cooperation of various environmental factors before it can be "expressed," but the same can be said of other kinds of message. An initial response might be to think that this mode of description is entirely anchored in a set of well-established facts about the role of DNA and RNA within protein synthesis, summarized in the familiar chart representing the "genetic code," mapping DNA base triplets to amino acids. However, informational enthusiasm in biology predates even a rudimentary understanding of these mechanisms (Schrodinger 1944). And more importantly, current applications of informational concepts extend far beyond anything that can receive an obvious justification in terms of the familiar facts about the specification of protein molecules by DNA. This includes: 1 (i) The description of whole-organism phenotypic traits (including complex behavioral traits) as specified or coded for by information contained in the genes, (ii) The treatment of many causal processes within cells, and perhaps of the wholeorganism developmental sequence, in terms of the execution of a program stored in the genes, (iii) The idea that genes themselves, for the purpose of evolutionary theorizing, should be seen as, in some sense, "made" of information.. (shrink)

Lockdowns and related policies of behavioral and economic restriction introduced in response to the COVID-19 pandemic are criticized, drawing on three sets of ideas and arguments that are organized in accordance with the likely degree of controversy associated with their guiding assumptions. The first set of arguments makes use of cost–benefit reasoning within a broadly utilitarian framework, emphasizing uncertainty, the role of worst-case scenarios, and the need to consider at least the medium term as well as immediate effects. The second (...) draws on assumptions about the political value of basic liberties. The third draws on ideas about the roles of different stages within human life. (shrink)

One problem faced in discussions of the evolution of intelligence is the need to get a precise fix on what is to be explained. Terms like "intelligence," "cognition" and "mind" do not have simple and agreed-upon meanings, and the differences between conceptions of intelligence have consequences for evolutionary explanation. I hope the papers in this volume will enable us to make progress on this problem. The present contribution is mostly focused on these basic and foundational issues, although the last section (...) of the paper will look at some specific models and programs of empirical work. (shrink)

Formal methods developed for modeling levels of selection problems have recently been applied to the investigation of major evolutionary transitions. We discuss two new tools of this kind. First, the ‘near-variant test’ can be used to compare the causal adequacy of predictively equivalent representations. Second, ‘state-variable gestalt-switching’ can be used to gain a useful dual perspective on evolutionary processes that involve both higher and lower level populations.

In evolution, large-scale changes that involve the origin of complex new traits occur gradually, in a broad sense of the term. This principle applies to the origin of subjective or felt experience. I respond to difficulties that have been raised for a gradualist view in this area, and sketch a scenario for the gradual evolution of subjective experience, drawing on recent research into early nervous system evolution.

I look back at my 1996 book Complexity and the Function of Mind in Nature, responding to papers by Pamela Lyon, Fred Keijzer and Argyris Arnellos, and Matt Grove.

Methods and goals in philosophy are discussed by first describing an ideal, and then looking at how the ideal might be approached. David Lewis’s work in metaphysics is critically examined and compared to analogous work by Mackie and Carnap. Some large-scale philosophical systematic work, especially in metaphysics, is best treated as model-building, in a sense of that term that draws on the philosophy of science. Models are constructed in a way that involves deliberate simplification, or other imaginative modification of reality, (...) in order to make relationships visible or problems tractable. (shrink)

Birch, Ginsburg, and Jablonka suggest that Unlimited Associative Learning is a “transition marker” in the evolutionary process that produced consciousness, and organizes research by tying together a range of “hallmarks” of consciousness. I argue that the features they recognize as “hallmarks” are indeed important in the evolution of consciousness, but UAL may have a more limited role.

An interpretation of John Dewey’s views about realism, science, and naturalistic philosophy is presented. Dewey should be seen as an unorthodox realist, with respect to both general metaphysical debates about realism and with respect to debates about the aims and achievements of science.

COVID-19 often manifests with different outcomes in different patients, highlighting the complexity of the host-pathogen interactions involved in manifestations of the disease at the molecular and cellular levels. In this paper, we propose a set of postulates and a framework for systematically understanding complex molecular host-pathogen interaction networks. Specifically, we first propose four host-pathogen interaction (HPI) postulates as the basis for understanding molecular and cellular host-pathogen interactions and their relations to disease outcomes. These four postulates cover the evolutionary dispositions involved (...) in HPIs, the dynamic nature of HPI outcomes, roles that HPI components may occupy leading to such outcomes, and HPI checkpoints that are critical for specific disease outcomes. Based on these postulates, an HPI Postulate and Ontology (HPIPO) framework is proposed to apply interoperable ontologies to systematically model and represent various granular details and knowledge within the scope of the HPI postulates, in a way that will support AI-ready data standardization, sharing, integration, and analysis. As a demonstration, the HPI postulates and the HPIPO framework were applied to study COVID-19 with the Coronavirus Infectious Disease Ontology (CIDO), leading to a novel approach to rational design of drug/vaccine cocktails aimed at interrupting processes occurring at critical host-coronavirus interaction checkpoints. Furthermore, the host-coronavirus protein-protein interactions (PPIs) relevant to COVID-19 were predicted and evaluated based on prior knowledge of curated PPIs and domain-domain interactions, and how such studies can be further explored with the HPI postulates and the HPIPO framework is discussed. (shrink)

The idea that innateness can be understood in terms of genetic coding or genetic programming is discussed. I argue that biology does not provide any support for the view that the whole-organism features of interest to nativists in psychology and linguistics are genetically coded for. This provides some support for recent critical and deflationary treatments of the concept of innateness.

Problems raised by complex life cycles for standard summaries of evolutionary processes, and for concepts of individuality in biology, are described. I then outline a framework that can be used to compare life cycles. This framework treats reproduction as a combination of production and recurrence and organizes life cycles according to the distribution of steps in which multiplication, bottlenecks, and sex occur. I also discuss fitness and its measurement in complex life cycles and consider some phenomena that raise complications and (...) difficulties for my framework. (shrink)

The Salivaomics Knowledge Base (SKB) is designed to serve as a computational infrastructure that can permit global exploration and utilization of data and information relevant to salivaomics. SKB is created by aligning (1) the saliva biomarker discovery and validation resources at UCLA with (2) the ontology resources developed by the OBO (Open Biomedical Ontologies) Foundry, including a new Saliva Ontology (SALO). We define the Saliva Ontology (SALO; http://www.skb.ucla.edu/SALO/) as a consensus-based controlled vocabulary of terms and relations dedicated to the salivaomics (...) domain and to saliva-related diagnostics following the principles of the OBO (Open Biomedical Ontologies) Foundry. The Saliva Ontology is an ongoing exploratory initiative. The ontology will be used to facilitate salivaomics data retrieval and integration across multiple fields of research together with data analysis and data mining. The ontology will be tested through its ability to serve the annotation ('tagging') of a representative corpus of salivaomics research literature that is to be incorporated into the SKB. Background Saliva (oral fluid) is an emerging biofluid for non-invasive diagnostics used in the detection of human diseases. The need to advance saliva research is strongly emphasized by the National Institute of Dental and Craniofacial Research (NIDCR), and is included in the NIDCR's 2004- 2009 expert panel long-term research agenda [1]. The ability to monitor health status, disease onset, progression, recurrence and treatment outcome through noninvasive means is highly important to advancing health care management. Saliva is a perfect medium to be explored for personalized individual medicine including diagnostics, offering a non-invasive, easy to obtain means for detecting and monitoring diseases. Saliva testing potentially allows the patient to collect their own saliva samples at home, yielding convenience for the patient and savings in health costs, and facilitating multiple sampling. Specimen collection is less objectionable to patients and easier in children and elderly individuals. Due to these advantages. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:The Journal of Aesthetic Education 39.4 (2005) 1-2 [Access article in PDF] A Personal Tribute to Nellie McCaslin: 20 August 1914–28 February 2005 Nellie McCaslin, pioneer in creative drama and educational theatre, passed away earlier this year in New York City at age 90. Having obtained a bachelor's degree from Western Reserve University in 1936 and a master's degree in 1937, she went on to study improvisation with Maria (...) Ouspenskaya, of the Moscow Art Theatre, in California. In 1957, she received a Ph.D. from the School of Education at New York University (NYU). A longtime Greenwich Village resident, she became associate dean at the Gallatin School of Individualized Study and for over thirty years was an adjunct faculty member at NYU's Program in Educational Theatre.Her publications include Theatre for Children in the United States: A History (1971), Children and Drama (1975), Theatre for Young Audiences (1978), and Creative Drama in the Classroom and Beyond (2006), forthcoming in its eighth edition. She will be fondly remembered by her colleagues and friends for her keynote speeches delivered at conferences and events from Canada to Switzerland, from Israel to Taiwan. Throughout her career, she enthusiastically encouraged imagination and creativity through creative drama and the arts. In 1977, she was elected to the American College of Fellows. She received an honorary Doctor of Humanities from Ferrum College, Virginia, in 1986. Nellie's outstanding contribution to educational theatre was recognized with a Lifetime Achievement Award from the American Alliance of Theatre and Education in 1996 and with a Medallion Award from the Children's Theatre Foundation in 2001.At the Program in Educational Theatre at NYU, she taught courses in Theatre for Young Audiences and Creative Drama. She would also invite [End Page 1] friends and acquaintances to attend seminars at her church, First Presbyterian in the Village, and afterwards we might return to her apartment on 10th Street, where she would introduce us to fellow artists. Nellie found time to volunteer at church and at the local animal shelter, Bide-A-Wee. Her tireless energy and compassion were expressions of her love of living. She had begun to act again and each summer would travel south to take part in the Blue Ridge Dinner Theatre. Artistic Director Rex Stephenson said recently, "She's the only person that could cash a check from New York in Rocky Mount, Virginia, because everybody knew who she was."1 People were drawn to Nellie, as if by her luminous presence; she always had time to listen. Active to the end, she wrote the article that appears in this issue of the Journal of Aesthetic Education. Before she died, Nellie was working with NYU students to create a new play. At St. Vincent's in Manhattan, she was rehearsing her lines by telephone from her hospital bed. She will be deeply missed. Alistair Martin-Smith Endnote 1. Margalit Fox, "Nellie McCaslin, Professor and Children's Theater Authority, Dies at 90," New York Times, 12 March 2005.Photo by Maya Ishiura... (shrink)

"Additive variance in fitness" is an important concept in the formal apparatus of population genetics. Wimsatt and Lloyd have argued that this concept can also be used to decide the "unit of selection" in an evolutionary process. The paper argues that the proposed criteria of Wimsatt and Lloyd are ambiguous, and several interpretations of their views are presented. It is argued that none of these interpretations provide acceptable criteria for deciding units of selection. The reason is that additive variance in (...) fitness can be both a cause of evolution, but also a byproduct of selection at another level. (shrink)

John Dewey’s Experience and Nature has the potential to transform several areas of philosophy. The book is lengthy and difficult, but it has great importance for a knot of issues in epistemology, metaphysics, and philosophy of mind. It bears also on metaphilosophy, devoting many pages to the discipline’s characteristic pathologies, and advancing a view of what sort of guidance “naturalism” provides. Later chapters move on to discuss art, morality, and value. So this is a major statement by Dewey. It may (...) one day transform moral philosophy as he hopes, but this review will focus on the central ideas of the first two-thirds of the book. Here Dewey does succeed, I think, in motivating us to look at his core topics—experience and nature—in a new way. And though Dewey’s language is often obscure and unhelpful, some of the main ideas are simpler than they look.Earlier “pragmatist” philosophical work was novel in its focus on the relation between thought and action. This work had a broadly emp. (shrink)

William Dembski holds that "the origin of information is best sought in intelligent causes" ("Intelligent Design as a Theory of Information", 1997). In particular, Dembski argues that Darwinism is not able to explain the existence of biological structures that contain a certain kind of information – "complex specified information" (CSI). To explain these informational features of living systems, we must instead appeal to the choices made by an intelligent designer.

Group-structured and neighbor-structured populations are compared, especially in relation to multilevel selection theory and evolutionary transitions. I argue that purely neighborstructured populations, which can feature the evolution of altruism, are not properly described in multilevel terms. The ability to “gestalt switch” between individualist and multilevel frameworks is then linked to the investigation of “major transitions” in evolution. Some explanatory concepts are naturally linked to one framework or the other, but a full understanding is best achieved via the use of both.

An interpretation is given of John Dewey's views about “realism” in metaphysics, and of how these views relate to contemporary debates. Dewey rejected standard formulations of realism as a general metaphysical position, and interpreters have often been taken him to be sympathetic to some form of verificationism or constructivism. I argue that these interpretations are mistaken, as Dewey's unease with standard formulations of realism comes from his philosophical emphasis on intelligent control of events, by means of ordinary action. Because of (...) his views about relations, Dewey's views in this area do risk collapsing into an overly holistic position. I discuss how these problems might be avoided, and consider also how Dewey's views about naturalism and realism might usefully inform ongoing work. (shrink)

Many vertebrate animals approximate, to various degrees, the “split‐brain” condition that results from surgery done in humans to treat severe epilepsy, with very limited connection between the left and right sides of the upper parts of the brain. The split‐brain condition has been the topic of extensive philosophical discussion, because it appears, in some circumstances, to give rise to two minds within one body. Is the same true of these animals? This article attempts to make progress on two difficult topics—animal (...) experience, and the consequences of the human split‐brain condition—by considering both at once. (shrink)

Jablonka and Lamb's claim that evolutionary biology is undergoing a ‘revolution’ is queried. But the very concept of revolutionary change has uncertain application to a field organized in the manner of contemporary biology. The explanatory primacy of sequence properties is also discussed.

My commentary on Hurley is concerned with foundational issues. Hurley's investigation of animal cognition is cast within a particular framework—basically, a philosophically refined version of folk psychology. Her discussion has a complicated relationship to unresolved debates about the nature and status of folk psychology, especially debates about the extent to which folk psychological categories are aimed at picking out features of the causal organization of the mind.

There is a need recognized by the National Institute of Dental & Craniofacial Research and the National Cancer Institute to advance basic, translational and clinical saliva research. The goal of the Salivaomics Knowledge Base (SKB) is to create a data management system and web resource constructed to support human salivaomics research. To maximize the utility of the SKB for retrieval, integration and analysis of data, we have developed the Saliva Ontology and SDxMart. This article reviews the informatics advances in saliva (...) diagnostics made possible by the Saliva Ontology and SDxMart. (shrink)

An interpretation is given of John Dewey's views about “realism” in metaphysics, and of how these views relate to contemporary debates. Dewey rejected standard formulations of realism as a general metaphysical position, and interpreters have often been taken him to be sympathetic to some form of verificationism or constructivism. I argue that these interpretations are mistaken, as Dewey's unease with standard formulations of realism comes from his philosophical emphasis on intelligent control of events, by means of ordinary action. Because of (...) his views about relations, Dewey's views in this area do risk collapsing into an overly holistic position. I discuss how these problems might be avoided, and consider also how Dewey's views about naturalism and realism might usefully inform ongoing work. (shrink)